In a small village in Oaxaca, where men, women and muxes live together, two very different boys Erik and Manuel are the sole witnesses to an unexpected death, a secret that makes their friendship unbreakable. Twenty years later, their paths cross again, but their differences are even greater: Erik now finds Sicarú, a woman. Together they will face the great secret of their past and their problems in the present, putting the power of friendship to the test.