Jo is a 41-year-old bisexual writer of LGBT fiction who is having a bad year. She is suffering from a case of writers block, struggles with a caffeine addiction and is currently mourning the loss of her wife from cancer. Wanting something different in her life, she asks her late wife's brother Jamie to be a sperm donor so she can get pregnant and raise a baby by herself. Adding to the craziness is Jo's visit to a fertility clinic's Dr. Laura Berg, and developing a love triangle romance with her two best friends, Nate and Lisa.