A pack of blood thirsty vampires attacks people in an American city. When their leader Alex Stone meets the mortal Estelle Henderson, they fall in love with each other and Alex seeks out her father, who is researching immortality, to ask him to be reverted to mortal again. The Illuminati Cartel is secretly sponsoring the researches since their leader Victor Price wants to be immortal. Meanwhile, the vampire hunter Marshall Pope arrives in the city to help the police to hunt down the vampires.